Type I interferon regulation by USP18 is a key vulnerability in cancer
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Jové V. et al, (2024), iScience, 27
Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells.
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Barnkob MB. et al, (2024), Nat Commun, 15
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
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Hamid MHBA. et al, (2024), Nat Immunol
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.
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Balıkçı E. et al, (2024), Journal of medicinal chemistry
Oncogenic cell tagging and single-cell transcriptomics reveal cell type-specific and time-resolved responses to Vhl inactivation in the kidney
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Kurlekar S. et al, (2024), Cancer Research
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1
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Imhoff RD. et al, (2024), Journal of Medicinal Chemistry
Lung Ultrasound Reproducibly Outperforms Computed Tomography in the Detection of Extravascular Lung Water in Patients Undergoing Haemodialysis
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Corcoran JP. et al, (2024), Diagnostics, 14, 589 - 589
A novel method to quantify fibrin-fibrin and fibrin-α2AP cross-links in thrombi formed from human trauma patient plasma
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Morrow GB. et al, (2024), Journal of Thrombosis and Haemostasis
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
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Ma J. et al, (2024), Proceedings of the National Academy of Sciences of the United States of America, 121
Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial.
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Bozbas E. et al, (2024), The American journal of clinical nutrition
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.
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Xiong Y. et al, (2024), Journal of medicinal chemistry
Optimized protocol for CRISPR knockout of human iPSC-derived macrophages.
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Navarro-Guerrero E. et al, (2024), STAR Protoc, 5
Protein Profiling of Placental Extracellular Vesicles in Gestational Diabetes Mellitus
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Kandzija N. et al, (2024), International Journal of Molecular Sciences, 25, 1947 - 1947
Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis
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Dellar ER. et al, (2024), Journal of Neurochemistry, 168, 115 - 127
Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors
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Lo Faro ML. et al, (2024), Kidney International Reports
Mechanisms of PAS Domain Signalling, from Sensing Varied Small Molecules and Peptides to Approved Pharmaceuticals and Use in Optogenetics.
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Khorasanizadeh S. and Gardner KH., (2024), J Mol Biol, 436
Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2
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Bradshaw WJ. et al, (2024), Structure
Tau depletion in human neurons mitigates Aβ-driven toxicity.
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Ng B. et al, (2024), Molecular psychiatry
Time, location and function of hypoxia-inducible factors are critical to therapeutic tumour response
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Marignol L. and Pugh CW., (2024), BMJ Oncology, 3, e000290 - e000290
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
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Tsukada K. et al, (2024), Molecular Cell