Dr. Nicola Ternette, together with Annalisa Nicastri and Robert Parker, is running a workflow in the TDI MS laboratory to analyse the MHC immunopeptidome - MHC class I & II derived antigens. This methodology can be applied to discover bacterial, parasite and viral, but also tumour and autoimmone antigens.
Eur J Immunol, 46 (1), Read more2016. Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells.
J Virol, 89 (11), Read more2015. Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells.
Arthritis Rheumatol, 66 (2), Read more2014. Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.