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Inosine pranobex enhances human NK cell cytotoxicity by inducing metabolic activation and NKG2D ligand expression.

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McCarthy MT. et al, (2020), European journal of immunology, 50, 130 - 137

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta cells

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Vergari E. et al, (2020), Nature Metabolism, 2, 32 - 40

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

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Vergari E. et al, (2019), Nature Communications, 10

Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production

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Knudsen JG. et al, (2019), Cell Metabolism, 29, 430 - 442.e4

Purine nucleotide metabolism regulates expression of human MICA.

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O'Callaghan C. et al, (2018), JOURNAL OF IMMUNOLOGY, 200

Purine nucleotide metabolism regulates expression of the human immune ligand MICA

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McCarthy MT. et al, (2018), Journal of Biological Chemistry, 293, 3913 - 3924

Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes

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Manuel AM. et al, (2017), Antioxidants & Redox Signaling, 27, 1281 - 1296

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes

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Adam J. et al, (2017), Cell Reports, 20, 3135 - 3148

Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance

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Nijhuis A. et al, (2017), Human Molecular Genetics, 26, 1552 - 1564

Increased Expression of the Diabetes GeneSOX4Reduces Insulin Secretion by Impaired Fusion Pore Expansion

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The Succinated Proteome of FH-Mutant Tumours

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Yang M. et al, (2014), Metabolites, 4, 640 - 654

Rare insights into cancer biology

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Adam J. et al, (2014), Oncogene, 33, 2547 - 2556

Rare insights into cancer biology

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Adam J. et al, (2014), Oncogene, 33, 2547 - 2556

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

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Singleton RS. et al, (2014), Proceedings of the National Academy of Sciences, 111, 4031 - 4036

A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

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Adam J. et al, (2013), Cell Reports, 3, 1440 - 1448

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

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Ternette N. et al, (2013), Cell Reports, 3, 689 - 700

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