Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection.
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Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
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Accessory ESCRT-III proteins are conserved and selective regulators of Rab11a-exosome formation.
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T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles
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Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism.
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Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation
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Local depletion of proteoglycans mediates cartilage tissue repair in an ex vivo integration model.
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Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.
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Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism.
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The effects of endogenously‐ and exogenously‐induced hyperketonemia on exercise performance and adaptation
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ABPP-HT*—Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods
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Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase.
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Author Correction: Assessing the degradation of ancient milk proteins through site-specific deamidation patterns.
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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
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FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
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Advancing mechanistic understanding and biomarker development in amyotrophic lateral sclerosis
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Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
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Tanudjojo B. et al, (2021), Nature Communications, 12
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
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Shorrocks A-MK. et al, (2021), Nature Communications, 12
Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
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Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling
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