Adán Pinto-Fernández
PhD
Translational studies of the ubiquitin system
Currently studying the functions of the Ubiquitin-Proteasome System (UPS) in disease using advanced mass spectrometry, proteomics and chemical biology as main tools. I have been involved in different drug discovery programs and I am particularly interested in finding the translational angle of my research.
Recent publications
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Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics
Journal article
Pinto-Fernández A. et al, (2019), Frontiers in Chemistry, 7
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Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting
Journal article
Olie CS. et al, (2019), iScience, 12, 318 - 332
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Human Platelet Protein Ubiquitylation and Changes following GPVI Activation
Journal article
Unsworth A. et al, (2019), Thrombosis and Haemostasis, 119, 104 - 116
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A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN
Journal article
Weber A. et al, (2017), Cell Chemical Biology, 24, 1299 - 1313.e7
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Molecular basis of USP7 inhibition by selective small-molecule inhibitors
Journal article
Turnbull AP. et al, (2017), Nature, 550, 481 - 486