Postdoctoral Research Scientist
Jenny Ward completed her first degree (MChem) in Chemistry at the University of Oxford in 2011, having completed her Masters research in the synthesis and biological evaluation of non-inositol based ligands for the IP3 receptor under the supervision of Dr Stuart Conway. From 2011 to 2016 she undertook an MRes and PhD in Chemical Biology at the ICB-CDT, Imperial College London. Under the supervision of Prof Ed Tate and Prof Eric Lam, her research involved the design and proteomic profiling of activity-based probes for studying cellular ubiquitination machinery. In June 2016 Jenny joined the Huber group at the Target Discovery Institute, where her current research focuses on the chemoproteomic identification of novel drug targets in multiple myeloma.
Re-evaluating the mechanism of action of α,β-unsaturated carbonyl DUB inhibitors b-AP15 and VLX1570: a paradigmatic example of unspecific protein crosslinking with Michael acceptor motif-containing drugs.
Ward JA. et al, (2020), Journal of Medicinal Chemistry
Discovery of an MLLT1/3 YEATS Domain Chemical Probe
Moustakim M. et al, (2018), Angewandte Chemie International Edition, 57, 16302 - 16307