What is Target Discovery?
Target discovery helps identifying drug targets, molecules or molecular interactions at a critical point in a disease-causing pathway that are predicted to being amenable to therapeutic manipulation. The centre aims to link recent advances in genetics, genomics, cell and chemical biology for improved drug target discovery. A more specific focus for refining and validating such targets will provide a better link between traditional "open ended" academic processes to biomedical research and the need of the pharmaceutical industry for accurately defined targets to accelerate drug development.
Research and core expertise
7 October 2019
Peter Ratcliffe, William Kaelin and Gregg Semenza share the 2019 Nobel Prize for or Physiology and Medicine. They discovered how cells sense and adapt to oxygen levels, findings that affect our day-to-day life from exercise, to being at high altitudes to our early development in the womb. Their work is leading to new treatments for anaemia and even cancer
7 March 2019
A single-cell based study from Prof Alison Simmons Lab describes clonic epithelial cell diversity in health and inflammatory bowel disease (IBD).