Mass Spectrometry is key technology for studying critical molecules and pathways. Defining molecular targets is crucial for the process of drug development.
In our group, we are focused on using proteomics, mass spectrometry and biochemical approaches to understand disease processes.
The group has expertise in proteomics based methodologies and hosts a platform containing a variety of chromatography equipment and mass spectrometers.
Kessler Group Sky Garden London Nov 2018
- For Non-Scientists
- Research Overview
- Mass Spectrometry
- Public Engagement
- Photo Gallery
- Virtual tour of the Kessler Lab
- Former Group Members
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts
Fielden J. et al, (2020), Nature Communications, 11
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions
Thézénas M-L. et al, (2020), Scientific Reports, 10
CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis
Thompson AG. et al, (2020), Clinical Proteomics, 17
An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress
Feneberg E. et al, (2020), Neurobiology of Disease, 144, 105050 - 105050
Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors
Cusack M. et al, (2020), Genome Research