Mass Spectrometry is key technology for studying critical molecules and pathways. Defining molecular targets is crucial for the process of drug development.
In our group, we are focused on using proteomics, mass spectrometry and biochemical approaches to understand disease processes.
Proteomics and Mass Spectrometry
The group has expertise in proteomics based methodologies and hosts a platform containing a variety of chromatography equipment and mass spectrometers.
Our team
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Benedikt Kessler
Professor of Biochemistry and Mass Spectrometry
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Philip Charles
Bioinformatician/Statistician
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Andreas Damianou
Postdoctoral Researcher
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Roman Fischer
Associate Professor and Head of Discovery Proteomics Facility
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Svenja Hester
Research Assistant (Maternity cover)
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Hannah Jones
Postdoctoral Researcher
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Darragh O'Brien
Postdoctoral Researcher
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Hannah Scott
Research Assistant
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Bohan Yu
Visiting Student
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Zhanru Yu
Research Assistant
- For Non-Scientists
- Research Overview
- Mass Spectrometry
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Publications
- Publications 2022
- Publications 2021
- Publications 2020
- Publications 2019
- Publications 2018
- Publications 2017
- Publications 2016
- Publications 2015
- Publications 2014
- Publications 2013
- Publications 2012
- Publications 2011
- Publications 2010
- Publications 2009
- Publications 2005-2008
- Publications 2001-2004
- Publications 1997-2000
- Public Engagement
- Photo Gallery
- Virtual tour of the Kessler Lab
- Contact
- News
- Collaborators
- Former Group Members
Selected publications
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SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses
Journal article
Wellington D. et al, (2023), Heliyon, e20076 - e20076
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Targeted Mass Spectrometry Reveals Interferon-Dependent Eicosanoid and Fatty Acid Alterations in Chronic Myeloid Leukaemia
Preprint
Scott HC. et al, (2023)
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Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model
Journal article
van Leeuwen LL. et al, (2023), British Journal of Pharmacology
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Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides
Journal article
O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609
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Targeted Mass Spectrometry Reveals Interferon-Dependent Eicosanoid and Fatty Acid Alterations in Chronic Myeloid Leukaemia
Preprint
Scott HC. et al, (2023)