Mass Spectrometry is key technology for studying critical molecules and pathways. Defining molecular targets is crucial for the process of drug development.
In our group, we are focused on using proteomics, mass spectrometry and biochemical approaches to understand disease processes.
Proteomics and Mass Spectrometry
The group has expertise in proteomics based methodologies and hosts a platform containing a variety of chromatography equipment and mass spectrometers.
Our team
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Benedikt Kessler
Professor of Biochemistry and Mass Spectrometry
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Georgina Berridge
Research Assistant
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Philip Charles
Bioinformatician/Statistician
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Andreas Damianou
Postdoctoral Researcher
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Sarah Flannery
Research Assistant in Proteomics
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Svenja Hester
Research Assistant
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Hannah Jones
Postdoctoral Researcher
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Zhu Liang
Postdoctoral Scientist
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Darragh O'Brien
Head of Structural & Mechanistic Proteomics
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Hannah Scott
Research Assistant
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Iolanda Vendrell
Technologly Lead, Discovery Proteomics SRF
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Zhanru Yu
Research Assistant
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Bohan Yu
Visiting Student
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Publications
- Publications 2025
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- Publications 2005-2008
- Publications 2001-2004
- Publications 1997-2000
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Recent publications
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Tracking E2-specific substrates
Jones HBL. et al, (2025), Nature Chemical Biology
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ATR-hippo drives force signaling to nuclear F-actin and links mechanotransduction to neurological disorders
Chatzifrangkeskou M. et al, (2025), Science Advances, 11
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Deep Learning Derived Adipocyte Size Reveals Adipocyte Hypertrophy is under Genetic Control
Jørsboe E. et al, (2025)
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Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
O’Brien DP. et al, (2025), Journal of Proteome Research, 24, 479 - 490
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Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2
Li HZ. et al, (2025), Nature Communications, 16