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Publications

Accessory ESCRT-III proteins are conserved and selective regulators of Rab11a-exosome formation.

Marie PP. et al, (2023), J Extracell Vesicles, 12

Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity

Fowkes MM. et al, (2023), Journal of Medicinal Chemistry

Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6

Dietz L. et al, (2023), Science

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region

Emmenegger M. et al, (2023), iScience, 26, 105928 - 105928

Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models

Rodriguez-Berriguete G. et al, (2023), Clinical Cancer Research

Discovery of a chemical probe to study implications of BPTF bromodomain inhibition in cellular and in vivo experiments.

Martinelli P. et al, (2023), ChemMedChem

Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia

Johanssen T. et al, (2023), Frontiers in Oncology, 12

Activity-Based Protein Profiling (ABPP) for Cellular Deubiquitinase (DUB) and Inhibitor Profiling at Deep and High-Throughput Levels.

Jones HBL. et al, (2023), Methods in molecular biology (Clifton, N.J.), 2591, 101 - 122

Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.

Londregan AT. et al, (2022), J Med Chem

A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.

Rottner AK. et al, (2022), Nature genetics

Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model

O’Brien DP. et al, (2022), Clinical Proteomics, 19

Nilabh Shastri – Towards understanding classical and non-classical MHC-I antigen processing and presentation

Kessler BM., (2022), Cellular Immunology, 382, 104638 - 104638

T cells are ready for the fight against monkeypox.

Wellington D. and Dong T., (2022), Cell host & microbe, 30, 1653 - 1654

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

Céspedes PF. et al, (2022), Nature Communications, 13

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature.

Lombardi O. et al, (2022), Cell reports, 41

Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.

Frank N. et al, (2022), Nature, 611, 721 - 726

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism.

Cavounidis A. et al, (2022), Mucosal immunology

KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity.

Fournier M. et al, (2022), eLife, 11

Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant.

Lou H. et al, (2022), Cell research

IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.

Clement M. et al, (2022), Nature communications, 13

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