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Publications

Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model

O’Brien DP. et al, (2022), Clinical Proteomics, 19

Nilabh Shastri – Towards understanding classical and non-classical MHC-I antigen processing and presentation

Kessler BM., (2022), Cellular Immunology, 382, 104638 - 104638

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

Céspedes PF. et al, (2022), Nature Communications, 13

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature.

Lombardi O. et al, (2022), Cell reports, 41

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism.

Cavounidis A. et al, (2022), Mucosal immunology

KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity.

Fournier M. et al, (2022), eLife, 11

Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant.

Lou H. et al, (2022), Cell research

Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane.

Frank N. et al, (2022), Nature

IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.

Clement M. et al, (2022), Nature communications, 13

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

Wing PAC. et al, (2022), PLOS Pathogens, 18, e1010807 - e1010807

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation

Zhou D. et al, (2022), Nature Communications, 13

The mechano-ubiquitinome of articular cartilage: Differential ubiquitination and activation of a group of ER-associated DUBs and ER stress regulators

Kaokhum N. et al, (2022), Molecular & Cellular Proteomics, 100419 - 100419

Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6

Cockman ME. et al, (2022), Proceedings of the National Academy of Sciences, 119

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.

Carling PJ. et al, (2022), Autophagy, 1 - 14

Local depletion of proteoglycans mediates cartilage tissue repair in an ex vivo integration model.

Merrild NG. et al, (2022), Acta biomaterialia

Automated 96-well format high throughput colony formation assay for siRNA library screen

Hatch SB. et al, (2022), STAR Protocols, 3, 101355 - 101355

Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.

Leissing TM. et al, (2022), The Journal of biological chemistry, 298

Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.

Diao X. et al, (2022), Nature communications, 13

Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines

Wei J. et al, (2022), Nature Medicine, 28, 1072 - 1082

Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism.

Downton P. et al, (2022), Proceedings of the National Academy of Sciences of the United States of America, 119

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