Data from GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner
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Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L
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Yang H. et al, (2024), Science Advances, 10
Hif-2α programmes oxygen chemosensitivity in chromaffin cells
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Prange-Barczynska M. et al, (2024), Journal of Clinical Investigation
Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors.
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Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination
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Paralogue-Selective Degradation of the Lysine Acetyltransferase EP300
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A ligand discovery toolbox for the WWE domain family of human E3 ligases.
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Münzker L. et al, (2024), Communications biology, 7
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.
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Kent D. et al, (2024), Hepatology (Baltimore, Md.)
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Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank.
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N-terminal cysteine acetylation and oxidation patterns may define protein stability
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Heathcote KC. et al, (2024), Nature Communications, 15
Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients
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Stieger A. et al, (2024), Metabolites, 14, 334 - 334
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response
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Mi Y. et al, (2024), Science Translational Medicine, 16