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Publications

Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia

Fayed HS. et al, (2023), International Journal of Molecular Sciences, 24, 14410 - 14410

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses

Wellington D. et al, (2023), Heliyon, e20076 - e20076

Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model

van Leeuwen LL. et al, (2023), British Journal of Pharmacology

Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells

Tian Y-M. et al, (2023), Journal of Biological Chemistry, 105156 - 105156

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609

The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system.

Fazazi MR. et al, (2023), Brain research bulletin

Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells

Athanasiadis P. et al, (2023), iScience, 26

GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner.

Wang Z. et al, (2023), Cancer Res

Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells

Chan DKH. et al, (2023), Cell Death Discovery, 9

Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation

Zenko D. et al, (2023), Science Advances, 9

A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases.

Cao Y. et al, (2023), Science China. Life sciences

COVID-19 vaccination, risk-compensatory behaviours, and contacts in the UK

Buckell J. et al, (2023), Scientific Reports, 13

Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection.

Bharucha T. et al, (2023), J Proteome Res

Protection against SARS-CoV-2 Omicron BA.4/5 variant following booster vaccination or breakthrough infection in the UK

Wei J. et al, (2023), Nature Communications, 14

DEcancer: Machine learning framework tailored to liquid biopsy based cancer detection and biomarker signature selection

Halner A. et al, (2023), iScience, 26, 106610 - 106610

Disparities in care and outcomes for primary liver cancer in England during 2008-2018: a cohort study of 8.52 million primary care population using the QResearch database.

Liao W. et al, (2023), EClinicalMedicine, 59

Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination.

Yin Z. et al, (2023), Cell reports, 42

Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice.

Ondrová K. et al, (2023), Nature communications, 14

Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.

Fowler SL. et al, (2023), bioRxiv

Open resources for chemical probes and their implications for future drug discovery

Balıkçı E. et al, (2023), Expert Opinion on Drug Discovery, 1 - 9

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