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Publications

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.

Peng Y. et al, (2020), Nature immunology

TargetDB: A target information aggregation tool and tractability predictor

De Cesco S. et al, (2020), PLOS ONE, 15, e0232644 - e0232644

Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death.

Cottone L. et al, (2020), Cancer Res

Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study.

Eyre DW. et al, (2020), eLife, 9

In Memoriam: Professor Huib Ovaa (1973-2020): A Uniquely Brilliant and Enthusiastic Scientist, a Pioneer in Chemical Biology and the Ubiquitin Field

Mulder MPC. and Kessler BM., (2020), Frontiers in Chemistry, 8

Deliberately Losing Control of C-H Activation Processes in the Design of Small Molecule Fragment Arrays Targeting Peroxisomal Metabolism.

Kahn Tareque R. et al, (2020), ChemMedChem

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

Oftedal B. et al, (2020)

Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300

Williams LM. et al, (2020), Proceedings of the National Academy of Sciences, 202004281 - 202004281

The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.

Hooftman A. et al, (2020), Cell metabolism

ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity

Wan X. et al, (2020), Biochemical and Biophysical Research Communications

USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation

Rusilowicz-Jones EV. et al, (2020), Life Science Alliance, 3, e202000768 - e202000768

A Semi-automated and Scalable 3D Spheroid Assay to Study Neuroblast Migration.

Ducker M. et al, (2020), Stem cell reports

Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable inDrosophila

Sepil I. et al, (2020), Proceedings of the National Academy of Sciences, 117, 17094 - 17103

Endothelial Oxygen Sensing in Alveolar Maintenance.

Hodson E. and Ratcliffe PJ., (2020), American journal of respiratory and critical care medicine

Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease.

Zhao Y. et al, (2020), JCI insight, 5

Digital pathology and artificial intelligence will be key to supporting clinical and academic cellular pathology through COVID-19 and future crises: the PathLAKE consortium perspective.

Browning L. et al, (2020), Journal of clinical pathology

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Fenech EJ. et al, (2020), eLife, 9

Role of digital pathology in diagnostic histopathology in the response to COVID-19: results from a survey of experience in a UK tertiary referral hospital

Browning L. et al, (2020), Journal of Clinical Pathology

Artificial intelligence-based morphological fingerprinting of megakaryocytes: a new tool for assessing disease in MPN patients.

Sirinukunwattana K. et al, (2020), Blood advances, 4, 3284 - 3294

Human cancer germline antigen-specific cytotoxic T cell-what can we learn from patient.

Abd Hamid M. et al, (2020), Cellular & molecular immunology, 17, 684 - 692

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