Cellular High Throughput Screening (HTS)

The HTS team of researchers is lead by Associate Professor Daniel Ebner. Major investment in the group has enabled the procurement of high-end, state-of-the-art screening equipment; consisting of liquid handling automation, multi-platform plate readers and high content imaging equipment. This investment results in the ability to produce highly complex and diverse screens.

The aim of the screening facility at the Target Discovery Institute is to provide collaborative research scientists access to comprehensive and cost-effective high throughput biochemical or cell-based assays, across small compound, CRISPR, and RNAi screening platforms.

A broad range of screens have been run in our facility and our scientists have extensive knowledge of all aspects of high throughput screening. The centre collaborates closely with each researcher and we are available for consultation from the earliest stages of assay conception. We will work closely with each investigator through assay development, optimization, and screening. Diverse drug set libraries totaling several thousand compounds, and genome-wide CRISPR and siRNA screening libraries, are currently available in-house.