Screening Scientist
Contact information
Research groups
Charline Giroud
Screening Scientist
Charline Giroud graduated with a PhD degree in Biochemistry, Cellular and Molecular Biology, specialized in Virology, from the School of Medicine of Montpelier, France (2012). She studied the role of cAMP-dependent protein kinase (PKA) incorporated in HIV-1 particle, in early steps of the virus life cycle and showed that PKA acts as a cofactor of reverse transcription initiation.
She worked at the Department of Paediatric Infectious Diseases at the School of Medicine of Emory University of Atlanta, USA (2013) as a postdoctoral fellow. Using high throughput screening strategy combined to cell-based assay development, she discovered and characterized new HIV-1 and Ebola virus entry inhibitors for HIV-1 and Ebola virus entry. She started in the assay development and screening team in May 2017.
She worked at the Department of Paediatric Infectious Diseases at the School of Medicine of Emory University of Atlanta, USA (2013) as a postdoctoral fellow. Using high throughput screening strategy combined to cell-based assay development, she discovered and characterized new HIV-1 and Ebola virus entry inhibitors for HIV-1 and Ebola virus entry. She started in the assay development and screening team in May 2017.
Recent publications
Covalent Inhibitors of S100A4 Block the Formation of a Pro-Metastasis Non-Muscle Myosin 2A Complex
Journal article
Giroud C. et al, (2024), Journal of Medicinal Chemistry, 67, 18943 - 18956
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3.
Journal article
Raux B. et al, (2024), Bioorganic & medicinal chemistry letters, 98
Turning high-throughput structural biology into predictive inhibitor design
Journal article
Saar KL. et al, (2023), Proceedings of the National Academy of Sciences, 120