Contact information
Research groups
Katherine England
Postdoctoral Researcher
Katherine holds a D.Phil. in Organic Chemistry from the University of Oxford for her work on inhibitors of epigenetic proteins. She has worked in drug discovery across a variety of disease areas and drug classes in industry and academia and has been a member of the medicinal chemistry team at the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) since 2015.
Katherine is a team leader in the medicinal chemistry group contributing to a range of projects in the ODDI portfolio.
Recent publications
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Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
O’Brien DP. et al, (2025), Journal of Proteome Research, 24, 479 - 490
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Crystal structure of Fatty Acid Thioesterase A bound by 129 fragments provides diverse development opportunities
Kot E. et al, (2024)
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MITOCHONDRIAL DYSFUNCTION IN NEUROSCIENCE: RECENT DEVELOPMENTS IN USP30 INHIBITORS
Worm K. et al, (2024), Medicinal Chemistry Reviews, 37 - 58
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Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
O’Brien DP. et al, (2024)
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Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides
O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609