Target discovery helps identifying drug targets, molecules or molecular interactions at a critical point in a disease-causing pathway that are predicted to being amenable to therapeutic manipulation. The centre aims to link recent advances in genetics, genomics, cell and chemical biology for improved drug target discovery. A more specific focus for refining and validating such targets will provide a better link between traditional "open ended" academic processes to biomedical research and the need of the pharmaceutical industry for accurately defined targets to accelerate drug development.
Many researchers within NDM are working on life-saving vaccines for a variety of serious illnesses, ranging from HIV to malaria, or improving existing vaccines to make them more effective. To mark WHO Immunization Week NDM spoke to two scientists about their research.