Target discovery helps identifying drug targets, molecules or molecular interactions at a critical point in a disease-causing pathway that are predicted to being amenable to therapeutic manipulation. The centre aims to link recent advances in genetics, genomics, cell and chemical biology for improved drug target discovery. A more specific focus for refining and validating such targets will provide a better link between traditional "open ended" academic processes to biomedical research and the need of the pharmaceutical industry for accurately defined targets to accelerate drug development.
Following the success of last year's 'afternoon tea' talks at the Cheltenham Literature Festival, the Nuffield Department of Medicine signed up as a Festival Partner for The Times Cheltenham Science Festival 2014. Over the 6 days of the festival, 45 volunteers from 5 different units took turns in running the NDM stall in the Discover Zone. There were roughly 1000 visitors to the stall each day.