What is Target Discovery?

Target discovery helps identifying drug targets, molecules or molecular interactions at a critical point in a disease-causing pathway that are predicted to being amenable to therapeutic manipulation. The centre aims to link recent advances in genetics, genomics, cell and chemical biology for improved drug target discovery. A more specific focus for refining and validating such targets will provide a better link between traditional "open ended" academic processes to biomedical research and the need of the pharmaceutical industry for accurately defined targets to accelerate drug development.

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Biomarker discovery for patients with malignant pleural effusion

Biomarker discovery for patients with malignant pleural effusion

Posted 15/06/2018

Ioannis Psallidas (Respiratory Medicine) and colleagues including members of the Target Discovery Institute  (TDI) (Benedikt Kessler Roman Fischer) have developed a score that predicts risk of death for a common metastasis of patients with malignant pleural effusion. Four proteins with a significant role in survival have been discovered, leading the road for new disease treatment. The PROMISE study results have been published in Lancet Oncology.

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