Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
Skip to main content

Known and potential aspirin metabolites were evaluated as inhibitors of oxygen-sensing hypoxia-inducible transcription factor (HIF) hydroxylases; some of the metabolites were found to stabilise HIF-alpha in cells.

Original publication

DOI

10.1039/b814440k

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

21/12/2008

Pages

6393 - 6395

Keywords

Aspirin, Dioxygenases, Enzyme Inhibitors, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular Structure, Spectrometry, Mass, Electrospray Ionization