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Chromosome band 10q24 is rich in genes involved in development, tumorigenesis, neurological disorders, hormone metabolism, and environmentally induced disease susceptibility. We have constructed an STS-based integrated physical and genetic map of 10q24 derived from the CEPH-Généthon mega-YAC contig data for this region. This map consists of 42 fluorescence in situ hybridization-mapped overlapping CEPH mega-YACs spanning approximately 15 Mb to which 49 STS markers have been assigned, including 24 Généthon CA repeat genetic markers, 10 known gene loci from the 10q24 region (IFI56, IDE, PDE6C, RBP4, CYP2C, CD39, DNTT, GOT1, WNT8B, and PAX2) and 11 additional expressed sequences of unknown function.

Original publication

DOI

10.1006/geno.1997.4809

Type

Journal article

Journal

Genomics

Publication Date

01/07/1997

Volume

43

Pages

85 - 88

Keywords

Chromosome Banding, Chromosome Mapping, Chromosomes, Artificial, Yeast, Chromosomes, Human, Pair 10, Dinucleotide Repeats, Genetic Markers, Humans, Sequence Tagged Sites