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Publications

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.

Liang Z. et al, (2024), Cell Rep, 43

Type I interferon regulation by USP18 is a key vulnerability in cancer

Jové V. et al, (2024), iScience, 27

Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.

Hamid MHBA. et al, (2024), Nat Immunol

Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1

Imhoff RD. et al, (2024), Journal of Medicinal Chemistry

Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis

Dellar ER. et al, (2024), Journal of Neurochemistry, 168, 115 - 127

Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function - A Pilot Study in Donation After Circulatory Death Donors

Lo Faro ML. et al, (2024), Kidney International Reports

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution

Tsukada K. et al, (2024), Molecular Cell

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism

Gan J. et al, (2023), Proceedings of the National Academy of Sciences, 120

211.5: Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model.

Leeuwen LV. et al, (2023), Transplantation, 107

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses

Wellington D. et al, (2023), Heliyon, e20076 - e20076

Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model

van Leeuwen LL. et al, (2023), British Journal of Pharmacology

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.

Carroll TM. et al, (2023), Cancer cell, 41, 1222 - 1241.e7

A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases.

Cao Y. et al, (2023), Science China. Life sciences

DEcancer: Machine learning framework tailored to liquid biopsy based cancer detection and biomarker signature selection

Halner A. et al, (2023), iScience, 26, 106610 - 106610

USP18 is an essential regulator of muscle cell differentiation and maturation

Olie CS. et al, (2023), Cell Death & Disease, 14

Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6

Dietz L. et al, (2023), Science, 379, 1112 - 1117

Activity-Based Protein Profiling (ABPP) for Cellular Deubiquitinase (DUB) and Inhibitor Profiling at Deep and High-Throughput Levels.

Jones HBL. et al, (2023), Methods in molecular biology (Clifton, N.J.), 2591, 101 - 122

Discovery of plasma proteome markers associated with clinical outcome and immunological stress after cardiac surgery

Bello C. et al, (2023), FRONTIERS IN CARDIOVASCULAR MEDICINE, 10

Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model

O’Brien DP. et al, (2022), Clinical Proteomics, 19

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