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Publications

Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages.

Navarro-Guerrero E. et al, (2021), Sci Rep, 11

Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.

Eyre DW. et al, (2021), BMC Infect Dis, 21

Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response.

Zhang P. et al, (2021), Cancer Res

Targeting IGF perturbs global replication through ribonucleotide reductase dysfunction

Rieunier G. et al, (2021), Cancer Research, canres.2860.2020 - canres.2860.2020

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification

Wells CI. et al, (2021), International Journal of Molecular Sciences, 22, 566 - 566

The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers.

Lumley SF. et al, (2021), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Chapter 7: Public-Private Partnerships to Advance Phenotypic Drug Discovery

Carragher N. et al, (2021), RSC Drug Discovery Series, 2021-January, 118 - 139

Community prevalence of SARS-CoV-2 in England from April to November, 2020: results from the ONS Coronavirus Infection Survey

Pouwels KB. et al, (2021), The Lancet Public Health, 6, e30 - e38

Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison

Ainsworth M. et al, (2020), The Lancet Infectious Diseases, 20, 1390 - 1400

Patient-derived malignant pleural mesothelioma cell cultures: a tool to advance biomarker-driven treatments

Kanellakis NI. et al, (2020), Thorax, 75, 1004 - 1008

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.

van de Weijer ML. et al, (2020), Molecular cell, 80, 374 - 375

ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity

Wan X. et al, (2020), Biochemical and Biophysical Research Communications, 531, 535 - 542

SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020.

Lumley SF. et al, (2020), Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 25

A Semi-automated and Scalable 3D Spheroid Assay to Study Neuroblast Migration.

Ducker M. et al, (2020), Stem cell reports, 15, 789 - 802

Adefovir dipivoxil induces DNA replication stress and augments ATR inhibitor‐related cytotoxicity

Patel A. et al, (2020), International Journal of Cancer, 147, 1474 - 1484

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

van de Weijer ML. et al, (2020), Molecular Cell, 79, 768 - 781.e7

Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

Eyre DW. et al, (2020), eLife, 9

HighVia—A Flexible Live-Cell High-Content Screening Pipeline to Assess Cellular Toxicity

Howarth A. et al, (2020), SLAS DISCOVERY: Advancing the Science of Drug Discovery, 25, 801 - 811

Transcriptomic and Functional Screens Reveal MicroRNAs That Modulate Prostate Cancer Metastasis

Rao SR. et al, (2020), Frontiers in Oncology, 10

CagA–ASPP2 complex mediates loss of cell polarity and favors H. pylori colonization of human gastric organoids

Buti L. et al, (2020), Proceedings of the National Academy of Sciences, 117, 2645 - 2655

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