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Publications

ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity

Wan X. et al, (2020), Biochemical and Biophysical Research Communications, 531, 535 - 542

A Semi-automated and Scalable 3D Spheroid Assay to Study Neuroblast Migration.

Ducker M. et al, (2020), Stem cell reports, 15, 789 - 802

Adefovir dipivoxil induces DNA replication stress and augments ATR inhibitor‐related cytotoxicity

Patel A. et al, (2020), International Journal of Cancer, 147, 1474 - 1484

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

van de Weijer ML. et al, (2020), Molecular Cell, 79, 768 - 781.e7

Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

Eyre DW. et al, (2020), eLife, 9

HighVia—A Flexible Live-Cell High-Content Screening Pipeline to Assess Cellular Toxicity

Howarth A. et al, (2020), SLAS DISCOVERY: Advancing the Science of Drug Discovery, 25, 801 - 811

Transcriptomic and Functional Screens Reveal MicroRNAs That Modulate Prostate Cancer Metastasis

Rao SR. et al, (2020), Frontiers in Oncology, 10

CagA–ASPP2 complex mediates loss of cell polarity and favors H. pylori colonization of human gastric organoids

Buti L. et al, (2020), Proceedings of the National Academy of Sciences, 117, 2645 - 2655

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib

Montenegro RC. et al, (2020), Oncotarget, 11, 535 - 549

The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification

Wells CI. et al, (2019)

Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression and drug response

Zhang P. et al, (2019)

E2F1 proteolysis via SCF ‐cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition

Burdova K. et al, (2019), The EMBO Journal, 38

A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function

Grotz AK. et al, (2019), Wellcome Open Research, 4, 150 - 150

Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets

Nizami S. et al, (2019), British Journal of Pharmacology, 176, 3515 - 3532

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions

Leng T. et al, (2019), Cell Reports, 28, 3077 - 3091.e5

Defining the Functional Role of NaV1.7 in Human Nociception

McDermott LA. et al, (2019), Neuron, 101, 905 - 919.e8

Cyclin F-Chk1 synthetic lethality mediated by E2F1 degradation

D'Angiolella V. et al, (2019)

A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6

Priestley RS. et al, (2019), Journal of Pharmacological and Toxicological Methods, 95, 47 - 55

Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer

Rebecca C. et al, (2019), Cancer Biology & Medicine, 16, 234 - 234

In vitro cancer models

Wan X. et al, (2019), Comprehensive Biotechnology, 550 - 559

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