Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination
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Sapmaz A. et al, (2024), Frontiers in Molecular Biosciences, 11
Deubiquitinases in muscle physiology and disorders
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Olie CS. et al, (2024), Biochemical Society Transactions, 52, 1085 - 1098
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
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Ellis MJ. et al, (2024), Acta neuropathologica, 147
Integrative multi-omics profiling in human decedents receiving pig heart xenografts.
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Schmauch E. et al, (2024), Nature medicine
Quantitative proteomics reveals CLR interactome in primary human cells
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Manolis D. et al, (2024), Journal of Biological Chemistry, 107399 - 107399
Tau depletion in human neurons mitigates Aβ-driven toxicity.
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Ng B. et al, (2024), Molecular psychiatry
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism
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Gan J. et al, (2023), Proceedings of the National Academy of Sciences, 120
Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides
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O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609
Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection
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Bharucha T. et al, (2023), Journal of Proteome Research, 22, 1614 - 1629
Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model
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O’Brien DP. et al, (2022), Clinical Proteomics, 19
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19
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Kotanidis CP. et al, (2022), The Lancet Digital Health, 4, e705 - e716
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
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Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58
Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19
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Vere G. et al, (2022), Biomolecules, 12, 300 - 300
A High-Affinity Calmodulin-Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells.
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Voegele A. et al, (2021), Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8
Subclinical effects of remote ischaemic conditioning in human kidney transplants revealed by quantitative proteomics
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Thorne AM. et al, (2020), Clinical Proteomics, 17
Hydrogen/Deuterium Exchange Mass Spectrometry for the Structural Analysis of Detergent-Solubilized Membrane Proteins.
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O'Brien DP. et al, (2020), Methods in molecular biology (Clifton, N.J.), 2127, 339 - 358
Post-translational acylation controls the folding and functions of the CyaA RTX toxin.
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O'Brien DP. et al, (2019), FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33, 10065 - 10076
Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) ofBordetella pertussis
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Voegele A. et al, (2018), Pathogens and Disease, 76
SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin.
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O'Brien DP. et al, (2018), Biotechnology and applied biochemistry, 65, 62 - 68
Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.
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O'Brien DP. et al, (2017), PLoS biology, 15