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Publications

Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1

Imhoff RD. et al, (2024), Journal of Medicinal Chemistry

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O'Brien DP. et al, (2023), Molecular & Cellular Proteomics, 22, 100609 - 100609

ABPP-HT*—Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods

Jones HBL. et al, (2022), International Journal of Molecular Sciences, 23, 3263 - 3263

Chemical Mapping Exposes the Importance of Active Site Interactions in Governing the Temperature Dependence of Enzyme Turnover

Winter SD. et al, (2021), ACS Catalysis, 11, 14854 - 14863

Sensing Enzyme Activation Heat Capacity at the Single-Molecule Level Using Gold-Nanorod-Based Optical Whispering Gallery Modes

Subramanian S. et al, (2021), ACS Applied Nano Materials, 4, 4576 - 4583

ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context.

Jones HBL. et al, (2021), Frontiers in chemistry, 9

Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift

Knight MJ. et al, (2020), Biochemical Journal, 477, 3599 - 3612

Include forthcoming?