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Publications

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.

Carling PJ. et al, (2022), Autophagy, 1 - 14

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.

Szykowska A. et al, (2021), Structure

A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6

Priestley RS. et al, (2019), Journal of Pharmacological and Toxicological Methods, 95, 47 - 55

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Rami HK. et al, (2006), Bioorganic & Medicinal Chemistry Letters, 16, 3287 - 3291

Discovery of small molecule antagonists of TRPV1

Rami HK. et al, (2004), Bioorganic & Medicinal Chemistry Letters, 14, 3631 - 3634

Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin.

Medhurst AD. et al, (2003), J Neurochem, 84, 1162 - 1172

TRPV3 is a temperature-sensitive vanilloid receptor-like protein

Smith GD. et al, (2002), Nature, 418, 186 - 190

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1

Trevisani M. et al, (2002), Nature Neuroscience, 5, 546 - 551

Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx.

Riccio A. et al, (2002), J Biol Chem, 277, 12302 - 12309

Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes.

Herdon HJ. et al, (2001), Neuropharmacology, 41, 88 - 96

Tacrine for Alzheimer's disease.

Qizilbash N. et al, (2000), Cochrane Database Syst Rev

An integrated physical and genetic map spanning chromosome band 10q24.

Gray IC. et al, (1997), Genomics, 43, 85 - 88

"Tackling gaps in developing life-changing treatments for dementia"

DAVIS J. et al, Alzheimer's and Dementia: Translational Research and Clinical Interventions

Include forthcoming?