HIF2α: the interface between oxygen-sensing systems in physiology and pathology
Bishop T. and Ratcliffe PJ., (2025), Physiology
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
Wing PAC. et al, (2022), PLOS Pathogens, 18, e1010807 - e1010807
Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.
Eckardt L. et al, (2021), Endocrine-related cancer, 28, 757 - 772
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
March-Diaz R. et al, (2021), Nature Aging, 1, 385 - 399
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Wing PAC. et al, (2021), Cell Reports, 35, 109020 - 109020
Silent hypoxaemia in COVID‐19 patients
Simonson TS. et al, (2021), The Journal of Physiology, 599, 1057 - 1065
Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control
Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251
Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4
Bishop T. and Ratcliffe PJ., (2020), Science Signaling, 13
Systemic silencing of Phd2 causes reversible immune regulatory dysfunction
Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656
PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies
Fielding JW. et al, (2018), The Journal of Physiology, 596, 4393 - 4412
Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2
Hulley PA. et al, (2017), The Journal of Pathology, 242, 322 - 333
Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice
Ratcliffe P. et al, (2016), Hypoxia, 69 - 69
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
Hodson EJ. et al, (2016), The Journal of Physiology, 594, 1179 - 1195
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
Chan MC. et al, (2015), PLOS ONE, 10, e0132004 - e0132004
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
Bishop T. and Ratcliffe PJ., (2015), Circulation Research, 117, 65 - 79
Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice
Livermore S. et al, (2015), 309 - 313
Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
Peter Ratcliffe P. and Bishop T., (2014), Hypoxia, 197 - 197
Benefits and risks of manipulating the HIF hydroxylase pathway in ischemic heart disease
Bishop T. and Ratcliffe PJ., (2013), Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment, 9780857299208, 17 - 25