HIF2α: the interface between oxygen-sensing systems in physiology and pathology
Bishop T. and Ratcliffe PJ., (2025), Physiology
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
Wing PAC. et al, (2022), PLOS Pathogens, 18, e1010807 - e1010807
Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences
Lee JY. et al, (2022), eLife, 11
Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.
Eckardt L. et al, (2021), Endocrine-related cancer, 28, 757 - 772
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
March-Diaz R. et al, (2021), Nature Aging, 1, 385 - 399
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Wing PAC. et al, (2021), Cell Reports, 35, 109020 - 109020
Silent hypoxaemia in COVID‐19 patients
Simonson TS. et al, (2021), The Journal of Physiology, 599, 1057 - 1065
Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control
Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251
Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4
Bishop T. and Ratcliffe PJ., (2020), Science Signaling, 13
Systemic silencing of Phd2 causes reversible immune regulatory dysfunction
Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656
PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies
Fielding JW. et al, (2018), The Journal of Physiology, 596, 4393 - 4412
Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2
Hulley PA. et al, (2017), The Journal of Pathology, 242, 322 - 333
Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice
Ratcliffe P. et al, (2016), Hypoxia, 69 - 69
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
Hodson EJ. et al, (2016), The Journal of Physiology, 594, 1179 - 1195
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
Chan MC. et al, (2015), PLOS ONE, 10, e0132004 - e0132004
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
Bishop T. and Ratcliffe PJ., (2015), Circulation Research, 117, 65 - 79
Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice
Livermore S. et al, (2015), 309 - 313
Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
Peter Ratcliffe P. and Bishop T., (2014), Hypoxia, 197 - 197
Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 allele and null for prolyl hydroxylase domain protein 1 (Men1+/-/Phd1-/-)
Stevenson M. et al, (2014), Endocrine Abstracts
Benefits and risks of manipulating the HIF hydroxylase pathway in ischemic heart disease
Bishop T. and Ratcliffe PJ., (2013), Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment, 9780857299208, 17 - 25