Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

Journal article

Cheng X. et al, (2020), Journal of Clinical Investigation, 130, 2237 - 2251

Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4

Journal article

Bishop T. and Ratcliffe PJ., (2020), Science Signaling, 13, eaba1302 - eaba1302

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

Journal article

Yamamoto A. et al, (2019), Journal of Clinical Investigation, 129, 3640 - 3656

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway

Journal article

Hodson EJ. et al, (2016), The Journal of Physiology, 594, 1179 - 1195

HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine

Journal article

Bishop T. and Ratcliffe PJ., (2015), Circulation Research, 117, 65 - 79

Augmented 5-HT Secretion in Pulmonary Neuroepithelial Bodies from PHD1 Null Mice

Journal article

Livermore S. et al, (2015), 309 - 313

Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives

Journal article

Peter Ratcliffe P. and Bishop T., (2014), Hypoxia, 197 - 197

Benefits and risks of manipulating the HIF hydroxylase pathway in ischemic heart disease

Chapter

Bishop T. and Ratcliffe PJ., (2013), Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment, 9780857299208, 17 - 25

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2

Journal article

Bishop T. et al, (2013), The Journal of Physiology, 591, 3565 - 3577

Hyperplasia of pulmonary neuroepithelial bodies (NEB) in lungs of prolyl hydroxylase -1(PHD-1) deficient mice

Journal article

Pan J. et al, (2012), Advances in Experimental Medicine and Biology, 758, 149 - 155

Benefits and Risks of Manipulating the HIF Hydroxylase Pathway in Ischemic Heart Disease

Chapter

Bishop T. and Ratcliffe PJ., (2012), Translational Vascular Medicine, 17 - 25

Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury

Journal article

Schneider M. et al, (2010), Gastroenterology, 138, 1143 - 1154.e2

Abnormal Sympathoadrenal Development and Systemic Hypotension in PHD3−/− Mice

Journal article

Bishop T. et al, (2008), Molecular and Cellular Biology, 28, 3386 - 3400

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

Journal article

Aragonés J. et al, (2008), Nature Genetics, 40, 170 - 180

Load More