Hif-2α programs oxygen chemosensitivity in chromaffin cells
Prange-Barczynska M. et al, (2024), Journal of Clinical Investigation, 134
N-terminal cysteine acetylation and oxidation patterns may define protein stability
Heathcote KC. et al, (2024), Nature Communications, 15
Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells
Tian Y-M. et al, (2023), Journal of Biological Chemistry, 105156 - 105156
Monitoring ADO dependent proteolysis in cells using fluorescent reporter proteins.
Smith E. and Keeley TP., (2023), 686, 267 - 295
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels.
Sevimli G. et al, (2022), Redox biology, 53
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Wing PAC. et al, (2021), Cell Reports, 35, 109020 - 109020
Defining Physiological Normoxia for Improved Translation of Cell Physiology to Animal Models and Humans.
Keeley TP. and Mann GE., (2019), Physiological reviews, 99, 161 - 234
Reduced SERCA activity underlies dysregulation of Ca2+ homeostasis under atmospheric O2 levels.
Keeley TP. et al, (2018), FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32, 2531 - 2538
A PP2A-mediated feedback mechanism controls Ca2+-dependent NO synthesis under physiological oxygen.
Keeley TP. et al, (2017), FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31, 5172 - 5183
Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels.
Chapple SJ. et al, (2016), Free radical biology & medicine, 92, 152 - 162