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Medicinal Chemistry
The Medicinal Chemistry group designs and synthesises chemical probes to interrogate the function of target proteins in cellular systems. The group is currently focused on discovering chemical probes for epigenetic proteins.
Alzheimer's Research UK Oxford Drug Discovery Institute
The Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) couples the deep disease knowledge and biology expertise of the academic community with high quality, innovative drug discovery technologies, to accelerate the discovery of novel, effective therapeutics for Alzheimer's disease and other neurodegenerative diseases.
TDI Mass Spectrometry Laboratory
Mass Spectrometry is key technology for studying critical molecules and pathways. Defining molecular targets is crucial for the process of drug development.
Chemical Biology
We are interested in the identification of novel drug targets using systems-level approaches such as phenotypic screens and chemical proteomics as well as the structure-based design of highly selective tool compounds for validation of new potential drug targets.
Cellular High Throughput Screening (HTS)
The HTS facility provides Oxford research scientists and collaborators access to comprehensive, cost-effective, high throughput cell-based small compound and CRISPR screens across a broad range of readouts.