Nicola Ternette
Dr, PhD
T-cell mediated immunity is reliant on the nature of the HLA-associated peptide pool presented on an infected cell or in tumour tissue. The specificity of this presentation determines the quality of the immunological response that can be elicited by cellular immune responses. My research focuses on qualitative and quantitative characterization of these cellular immunopeptidomes in the context of pathogen infection and cancer using mass spectrometry.
Recent publications
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Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells.
Journal article
Parker R. et al, (2021), Cell reports, 35
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Incoming HIV virion-derived Gag Spacer Peptide 2 (p1) is a target of effective CD8+ T cell antiviral responses.
Journal article
Yang H. et al, (2021), Cell reports, 35
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Integral Use of Immunopeptidomics and Immunoinformatics for the Characterization of Antigen Presentation and Rational Identification of BoLA-DR-Presented Peptides and Epitopes.
Journal article
Fisch A. et al, (2021), Journal of immunology (Baltimore, Md. : 1950)
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HLA binding of self-peptides is biased towards proteins with specific molecular functions
Journal article
Karnaukhov V. et al, (2021)
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Reply.
Journal article
Powell Doherty RD. et al, (2021), Gastroenterology, 160, 471 - 472