Mass Spectrometry is key technology for studying critical molecules and pathways. Defining molecular targets is crucial for the process of drug development.
In our group, we are focused on using proteomics, mass spectrometry and biochemical approaches to understand disease processes.
Proteomics and Mass Spectrometry
The group has expertise in proteomics based methodologies and hosts a platform containing a variety of chromatography equipment and mass spectrometers.
Our team
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Benedikt Kessler
Professor of Biochemistry and Mass Spectrometry
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Roman Fischer
Associate Professor and Head of Discovery Proteomics Facility
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Georgina Berridge
Research Assistant
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Philip Charles
Bioinformatician/Statistician
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Andreas Damianou
Postdoctoral Researcher
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Simon Davis
Postdoctoral Researcher
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Sarah Flannery
Research Assistant in Proteomics
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Svenja Hester
Research Assistant
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Hannah Jones
Postdoctoral Researcher
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Zhu Liang
Postdoctoral Scientist
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Darragh O'Brien
Head of Structural & Mechanistic Proteomics
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Hannah Scott
Research Assistant
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Iolanda Vendrell
Technologly Lead, Discovery Proteomics SRF
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Zhanru Yu
Research Assistant
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Bohan Yu
Visiting Student
- For Non-Scientists
- Research Overview
- Mass Spectrometry
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Publications
- Publications 2024
- Publications 2023
- Publications 2022
- Publications 2021
- Publications 2020
- Publications 2019
- Publications 2018
- Publications 2017
- Publications 2016
- Publications 2015
- Publications 2014
- Publications 2013
- Publications 2012
- Publications 2011
- Publications 2010
- Publications 2009
- Publications 2005-2008
- Publications 2001-2004
- Publications 1997-2000
- Public Engagement
- Photo Gallery
- Virtual tour of the Kessler Lab
- Contact
- News
- Collaborators
- Former Group Members
Recent publications
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Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex
Journal article
Damianou A. et al, (2024), Life Science Alliance, 7, e202302245 - e202302245
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Type I interferon regulation by USP18 is a key vulnerability in cancer
Journal article
Jové V. et al, (2024), iScience, 27
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Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Journal article
Hamid MHBA. et al, (2024), Nat Immunol
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Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1
Journal article
Imhoff RD. et al, (2024), Journal of Medicinal Chemistry
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Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial.
Journal article
Bozbas E. et al, (2024), The American journal of clinical nutrition