Mass Spectrometry is key technology for studying critical molecules and pathways. Defining molecular targets is crucial for the process of drug development.
In our group, we are focused on using proteomics, mass spectrometry and biochemical approaches to understand disease processes.
Proteomics and Mass Spectrometry
The group has expertise in proteomics based methodologies and hosts a platform containing a variety of chromatography equipment and mass spectrometers.
Our team
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Benedikt Kessler
Professor of Biochemistry and Mass Spectrometry
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Georgina Berridge
Research Assistant
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Philip Charles
Bioinformatician/Statistician
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Andreas Damianou
Postdoctoral Researcher
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Sarah Flannery
Research Assistant in Proteomics
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Svenja Hester
Research Assistant
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Hannah Jones
Postdoctoral Researcher
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Zhu Liang
Postdoctoral Scientist
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Darragh O'Brien
Head of Structural & Mechanistic Proteomics
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Hannah Scott
Research Assistant
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Iolanda Vendrell
Technologly Lead, Discovery Proteomics SRF
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Zhanru Yu
Research Assistant
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Bohan Yu
Visiting Student
- For Non-Scientists
- Research Overview
- Mass Spectrometry
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Publications
- Publications 2024
- Publications 2023
- Publications 2022
- Publications 2021
- Publications 2020
- Publications 2019
- Publications 2018
- Publications 2017
- Publications 2016
- Publications 2015
- Publications 2014
- Publications 2013
- Publications 2012
- Publications 2011
- Publications 2010
- Publications 2009
- Publications 2005-2008
- Publications 2001-2004
- Publications 1997-2000
- Public Engagement
- Photo Gallery
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- Contact
- News
- Collaborators
- Former Group Members
Recent publications
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Protocol to profile spatially resolved NLRP3 inflammasome complexes using APEX2-based proximity labeling
Journal article
Liang Z. et al, (2024), STAR Protocols, 5, 103417 - 103417
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Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease
Journal article
Fowler SL. et al, (2024), Nature Neuroscience
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Placental small extracellular vesicles from normal pregnancy and gestational diabetes increase insulin gene transcription and content in β cells
Journal article
Seedat F. et al, (2024), Clinical Science, 138, 1481 - 1502
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Elevated Cerebrospinal Fluid Ubiquitin Carboxyl‐Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers
Journal article
Dellar ER. et al, (2024), Annals of Neurology
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Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
Preprint
Scott HC. et al, (2024)