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The solid phase synthesis of the known proteasome inhibitor ZL3VS, using Kenner's safety catch protocol, is described. This methodology has been extended to the synthesis of various novel peptide vinyl sulfone and peptide epoxyketone derivatives. (C) 2000 Elsevier Science Ltd.

Original publication

DOI

10.1016/S0040-4039(00)00968-0

Type

Journal article

Journal

Tetrahedron Letters

Publication Date

05/08/2000

Volume

41

Pages

6005 - 6009